NUCLEIC ACIDS REGULATING OESTROGEN RECEPTOR (ER)-α SIGNALING IN BREAST CANCER

摘要

This invention relates to use of a nucleic acid or nucleic acids, preferably mi RNAs disclosed for the manufacture of a medicine for the treatment of breast cancer. This method also relates to a method of obtaining a marker value or values useful for differentiating patients with an oestrogen dependent breast cancer with an increased risk of progression into an oestrogen independent breast cancer by determining from a sample or samples of a tumour of breast cancer mi RNAs disclosed and establishing a marker value and/or values, which are a determined amount or amounts as such, or a function of the determined amount or amounts of disclosed mi RNAs. This invention also relates to a method of treatment and/or prevention of breast cancer.