USE OF HAPTOGLOBIN GENOTYPING IN DIAGNOSIS AND TREATMENT OF DEFECTIVE REVERSE CHOLESTEROL TRANSPORT (RCT)

摘要

A method of determining a potential of a nondiabetic or diabetic patient to benefit from reverse cholesterol transport therapy for treatment of a vascular complication, followed by methods and compositions of treating the diagnosed vascular complications comprising determining a haptoglobin phenotype of the patient. Reverse cholesterol transport therapy includes inhibition of cholesteryl ester transport protein, such as by using the compound torcetrapib.