首页> 外国专利> DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF

DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF

机译:编码特定L-阿拉伯糖转运蛋白,cDNA分子,包含所述DNA序列的质粒,用这种质粒转化的宿主细胞的DNA序列及其应用

摘要

The present invention refers to host cells genetically modified microorganisms by introducing a nucleic acid sequence encoding a specific L-arabinose transporter from yeast. The host cells are preferably those of an eukaryotic microorganism such as yeasts or filamentous fungi. The invention is useful for the complete use of sugar obtained from plant biomass and other ligno-cellulose materials of biotechnological importance in the production of biofuels, bulk and platform chemicals including ethanol, butanol, lactate, 1,4-diacids (succinate, fumaric, malic), glycerol, sorbitol, mannitol, xylitol/arabinitol, L-ascorbic acid, xylitol, hydrogen gas, 2,5-furan dicarboxylic acid, 3-hydroxy propionic acid, aspartic acid, glutaric acid, glutamic acid, itaconic acid, levulinic acid, and 3-hydroxybutyrolactone, fatty acids, fatty-derived molecules, isoprenoids, isoprenoid-derived molecules, alkanes, isopentanol, isoamylacetate, using genetically-modified microorganisms to consume and ferment L-arabinose in hexose and pentose mixtures resulting from renewable raw materials.
机译:本发明涉及通过从酵母导入编码特异性L-阿拉伯糖转运蛋白的核酸序列而对宿主细胞进行了基因修饰的微生物。宿主细胞优选是真核微生物如酵母或丝状真菌的那些。本发明可用于从植物生物质和具有生物技术重要性的其他木质纤维素材料中获得的糖在生物燃料,散装和平台化学品(包括乙醇,丁醇,乳酸,1,4-二酸(琥珀酸,富马酸,苹果酸),甘油,山梨糖醇,甘露糖醇,木糖醇/阿拉伯糖醇,L-抗坏血酸,木糖醇,氢气,2,5-呋喃二羧酸,3-羟基丙酸,天冬氨酸,戊二酸,谷氨酸,衣康酸,乙酰丙酸酸和3-羟基丁内酯,脂肪酸,脂肪衍生分子,类异戊二烯,类异戊二烯衍生分​​子,烷烃,异戊醇,异戊乙酸酯,使用转基因微生物消耗和发酵可再生原料制得的己糖和戊糖混合物中的L-阿拉伯糖。

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