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RELEASE OF ANTIBIOTIC FROM INJECTABLE, BIODEGRADABLE POLYURETHANE SCAFFOLDS FOR ENHANCED BONE FRACTURE HEALING
RELEASE OF ANTIBIOTIC FROM INJECTABLE, BIODEGRADABLE POLYURETHANE SCAFFOLDS FOR ENHANCED BONE FRACTURE HEALING
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机译:从可注射的,可生物降解的聚氨酯支架上释放抗生素,以增强骨骨折愈合
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摘要
A biodegradable polyurethane scaffold, comprising at least one polyisocyante, polyisocyanate prepolymer, or both, at least one polyester polyol, at least one catalyst, wherein the density of said scaffold is from about 50 to about 250 kg m-3 and the porosity of the scaffold is greater than about 70 (vol %) and at least 50% of the pores are interconnected with another pore, and wherein the scaffold incorporates at least one biologically active component in powder form.
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机译:一种可生物降解的聚氨酯支架,包含至少一种多异氰酸酯,多异氰酸酯预聚物或两者,至少一种聚酯多元醇,至少一种催化剂,其中所述支架的密度为约50至约250 kg m-3,且孔隙率为支架大于约70(体积%),并且至少50%的孔与另一个孔相互连接,并且其中所述支架包含至少一种粉末形式的生物活性组分。
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