首页> 外国专利> METHOD AND KIT FOR MEASUREMENT OF ACROLEIN ADDUCT IN SAMPLE UTILIZING AGGLUTINATION REACTION OF IMMUNOLOGICAL MICROPARTICLE

METHOD AND KIT FOR MEASUREMENT OF ACROLEIN ADDUCT IN SAMPLE UTILIZING AGGLUTINATION REACTION OF IMMUNOLOGICAL MICROPARTICLE

机译:利用免疫微颗粒凝聚反应的样品中阿考林素含量的测定方法和试剂盒

摘要

The method for measuring an acrolein adduct present in a sample according to the present invention comprising the steps of: (a) mixing a sample containing the acrolein adduct with a solution comprising an immunoglobulin that specifically recognizes the acrolein adduct; (b) adding to the mixture obtained in the step (a), a solution comprising microparticles to which a substance that specifically binds to the immunoglobulin that specifically recognizes the acrolein adduct and a blocking agent have been bound, and mixing them; and (c) measuring an extent of an agglutination reaction of the microparticles in the mixture obtained in the step (b), wherein the extent of the agglutination reaction being decreased relative to an amount of the acrolein adduct in the sample. The present invention enables a measurement of an acrolein adduct without requiring a complex operation.
机译:根据本发明的用于测量样品中存在的丙烯醛加合物的方法包括以下步骤:(a)将含有丙烯醛加合物的样品与包含特异性识别丙烯醛加合物的免疫球蛋白的溶液混合; (b)在上述步骤(a)中得到的混合物中,加入结合了微粒的溶液,该微粒结合有与特异性识别丙烯醛加合物的免疫球蛋白特异性结合的物质和封闭剂。 (c)测量在步骤(b)中获得的混合物中的微粒的凝集反应的程度,其中所述凝集反应的程度相对于样品中丙烯醛加合物的量降低。本发明能够测量丙烯醛加合物而无需复杂的操作。

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