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A vector for expressing antibody fragments and a method for producing recombinant phage that displays antibody fragments by using the vector

机译:表达抗体片段的载体和通过使用该载体生产展示抗体片段的重组噬菌体的方法

摘要

The present invention is a plasmid vector (pLT pLA-1 or-2) and a heavy chain antibody fragment (VH + CH1) -ΔpIII fusion protein expression and genotype for the production of water-soluble light chain antibody fragment (VL + CL) - phage associated with a phenotype feature mid Vector (pHf1g3T pHf1g3A-1 or-2), it relates to the recombinant phage by using a vector that displays the antibody and soluble antibody as a host and the host was transformed to a method for producing and screening. ; Soluble antibody fragments, vector, plasmid, phagemid, phage display
机译:本发明是用于生产水溶性轻链抗体片段(VL + CL)的质粒载体(pLT pLA-1或-2)和重链抗体片段(VH + CH1)-ΔpIII融合蛋白的表达和基因型。 -与表型特征中间载体(pHf1g3T pHf1g3A-1或-2)有关的噬菌体,它涉及通过使用以抗体和可溶性抗体为宿主的载体将重组噬菌体转化为生产和筛选。 ;可溶性抗体片段,载体,质粒,噬菌粒,噬菌体展示

著录项

  • 公开/公告号KR100958308B1

    专利类型

  • 公开/公告日2010-05-19

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20070103483

  • 发明设计人 차상훈;

    申请日2007-10-15

  • 分类号C12N15/64;

  • 国家 KR

  • 入库时间 2022-08-21 18:31:14

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