AGENTS FOR REPAIRING DAMAGE TO TRANSLANTED ISLANDS AFTER ISLAND TRANSPLANTATION

摘要

1. An agent for suppressing damage to a transplanted islet after islet transplantation, which includes an IL-6 inhibitor as an active ingredient. ! 2. An agent for suppressing damage to a transplanted islet according to claim 1, wherein the IL-6 inhibitor is an antibody that recognizes IL-6. ! 3. The agent for suppressing damage to the transplanted islet according to claim 1, wherein the IL-6 inhibitor is an antibody that recognizes the IL-6 receptor. ! 4. Agent for the suppression of damage to the transplanted islet according to claim 2 or 3, in which the antibody is a monoclonal antibody. ! 5. An agent for suppressing damage to a transplanted islet according to claim 2 or 3, wherein the antibody is an anti-human IL-6 antibody or an anti-human IL-6 receptor antibody. ! 6. An agent for suppressing damage to a transplanted islet according to claim 2 or 3, wherein the antibody is a recombinant antibody. ! 7. The agent for suppressing damage to the transplanted islet according to claim 6, in which the antibody is a chimeric, humanized antibody or a human antibody. ! 8. An agent for suppressing damage to a transplanted islet according to claim 2 or 3, used to treat diabetes. ! 9. A method of suppressing damage to transplanted islets in a subject with islet transplantation, which comprises the step of administering an IL-6 inhibitor to the subject. ! 10. A method of increasing islet viability in a subject with islet transplantation, which comprises the step of administering an IL-6 inhibitor to the subject. ! 11. The method according to claim 9 or 10, in which the inhibitor of IL-6 is an antibody that recognizes IL-6. ! 12. The method according to claim 9 or 10, in which the inhibitor of IL-6 is �