STRAIN OF HYBRID CULTIVATED MURINE CELLS Mus Musculus - 4F11 PRODUCING MONOCLONAL ANTIBODY RESPONDER WITH HEMAGGLUTININ PROTEIN OF HIGH-PATHOGEN STRAIN virus A/duck/Novosibirsk/56/05 H5N1AND UTILIZED FOR DIAGNOSTICS, PREVENTIVE MAINTENANCE AND TREATMENT

摘要

FIELD: medicine.;SUBSTANCE: invention concerns production of strain of hybrid cells Mus. Musculus 4F11 - producer of monoclonal antibody to hemagglutinin protein of avian influenza virus A/duck/Novosibirsk/56/05. There is prepared hybrid strain by fusing murine myeloma cells (Sp2/0) with murine spleen cells BALB/c, immunised with purified and inactivated preparation of avian influenza virus A/H5N1 strain A/duck/Novosibirsk/56/05. Strain of hybrid cells Mus. Musculus 4F11 is deposited in the Collection of cell culture of Ivanovsky State Research Institution of Virology of the Russian Academy of Medical Sciences, No. 8/2/2. The author's name of hybridoma cell line is 4F11.;EFFECT: invention allows preparing strain of hybrid cells 4F11, producing monoclonal antibodies to hemagglutinin protein of avian influenza virus A/H5N1.;1 dwg, 6 ex