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METHOD OF OBTAINING EXTRACT FROM CYSTS, OR NAUPLYS OR ADULT SPECIES OF SMALL CRUSTACEAN Artemia salina FOR EXTERNAL OR INTERNAL USE

机译:从小,青蟹卤虫的囊肿,NAUPS或成年物种中获取提取物以供外部或内部使用的方法

摘要

1. A process for preparing an extract from cysts or nauplii or adults crustacean Artemia Salina for external or internal use comprising forming a mixture of ultrafine powder of cysts or nauplii or adults crustacean Artemia Salina with a polar extractant in the form of aqueous or aqueous-glycerol solution with a starting content of the polar extractant for at least 40 wt.%, conducting multiple extraction with an extractant updating with stirring, filtering the extract and combining parts, removing the precipitate from the extract and distilling off the Artemia polar extractant, followed by storage of the finished extract or obtain on its base formulations by introducing special additives, characterized in that, before preparation of extracting a mixture of starting components to polar extractive solvent is added non-polar extractant at a ratio of at least 1: 1 and a solubilizer with a hydrophilic-lipophilic balance not less than 12.0 and the content in the mixture of extractants not more than 7.0 wt.%, the ratio of soot from cysts or nauplii or adults crustacean Artemia salina and prepared d mixtures of extractants with solubilizer is less than 1: 5, the content of the polar extractant in an aqueous or aqueous-glycerol solution when it is updated during the multiple feed extraction successively increased from 40 to 70 wt% before distilling the polar extractant extract is separated into hydrophilic and lipophilic. fraction by settling for at least 5 hours and discharging the lipophilic fraction and distilling off the solvent was subjected to a hydrophilic polar product fraction. ! 2. A method according to claim 1, characterized in that as polar
机译:1.一种从囊肿或无节幼体或成年的甲壳动物卤虫中提取的提取物,以供内用或外用,包括形成超细粉末的囊肿或无节幼体或成年的甲壳动物卤虫与水或水-极性萃取剂的起始含量至少为40 wt。%的甘油溶液,用萃取剂进行多次萃取,并随着搅拌进行更新,过滤萃取物并合并部分,从萃取物中除去沉淀物并蒸馏出Artemia极性萃取剂,然后通过储存最终的提取物或通过引入特殊添加剂在其基础制剂上获得其特征,其特征在于,在制备提取物之前,将起始组分与极性萃取溶剂的混合物以至少1:1的比例添加非极性萃取剂,并亲水亲脂平衡不低于12.0且萃取剂混合物中的含量不高于如果含量低于7.0 wt。%,则来自囊肿或无节幼体或成年甲壳类卤虫的烟灰与提取剂与增溶剂的混合混合物的烟灰比小于1:5,极性提取剂在水性或水性甘油溶液中的含量低于它在多次进料萃取过程中进行了更新,从40 wt%依次增加到70 wt%,然后将极性萃取剂的馏出物分为亲水性和亲脂性。通过沉降至少5小时并排出亲脂性馏分并蒸馏除去溶剂,使该馏分经历亲水性极性产物馏分。 ! 2.根据权利要求1的方法,其特征在于为极性

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