PHARMACEUTICAL COMPOSITION OF A PROTON PUMP INHIBITOR AND PREBIOTIC FOR TREATMENT OF ULCER OF THE STOMACH AND 12-FINGER GUT

摘要

1. A pharmaceutical composition for the treatment of gastric ulcer and duodenal ulcer, comprising at least one proton pump inhibitor (PPI) and at least one prebiotic in the following content of the components of the composition in wt.%:! proton pump inhibitor 0.05-25% prebiotic 40-95% excipients up to 100%! 2. The pharmaceutical composition according to claim 1, characterized in that it contains a prebiotic from the group of aliphatic alcohols: xylitol, sorbitol, lactitol. ! 3. The pharmaceutical composition according to claim 1, characterized in that it contains a prebiotic from the group of di- and trisaccharides: lactulose, lactosucrosis, melibiosis, xylobiosis, stachyosis, raffinosis. ! 4. The pharmaceutical composition according to claim 1, characterized in that it contains a prebiotic from the group of oligosaccharides: fructo-oligosaccharide, galactooligosaccharide, maltooligosaccharide, xylo-oligosaccharide, isomaltooligosaccharide, gentioligosaccharide. ! 5. The pharmaceutical composition according to claim 1, characterized in that it contains a prebiotic from the group of polysaccharides: arabinogalactan, pectins, pullulan, inulin, lignin. ! 6. The pharmaceutical composition according to any one of claims 1 to 5, characterized in that it contains a proton pump inhibitor from the group: omeprazole, pantoprazole, lansoprazole, rabeprazole and esomeprazole. ! 7. The pharmaceutical composition according to claim 6, characterized in that it contains an omeprazole proton pump inhibitor in an amount of 10-120 mg. ! 8. The pharmaceutical composition according to claim 6, characterized in that it contains a protopump inhibitor pantoprazole in an amount of 20-800 mg. ! 9. The pharmaceutical composition according to claim 6, characterized in that it contains a proton pump inhibitor lansoprazole in an amount of 10-600 mg. ! 10. Pharmaceutical Comp