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MEDICAL COMPOSITION FOR TREATING MUSCULAR ATROPHY AND ASTHENIC BULBAR PARALYSIS AND METHOD FOR PREPARING THEREOF
MEDICAL COMPOSITION FOR TREATING MUSCULAR ATROPHY AND ASTHENIC BULBAR PARALYSIS AND METHOD FOR PREPARING THEREOF
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机译:用于治疗肌萎缩和球囊麻痹的药物组合物及其制备方法
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摘要
FIELD: medicine.;SUBSTANCE: composition contains active ingredients extracted from herbs in the ratio 1-10 weight parts of ginseng and 1-10 weight parts Epimedium. Injections, capsule, pill, tablet or oral liquid. The following stages are performed: (1) herbs are weighed out; (2) ginseng is extracted for 1-3 times with alcohol 60 to 90%; the prepared extracts are mixed, filtered and concentrated; purified water is added to the concentrated solution to be mixed to a homogeneous solution; then the mixture is cooled and filtered; a diluted filtrate is introduced in a column absorber to be eluted with an aqueous eluant and alcohol 70% to 90%; an eluate is collected and decontaminated, concentrated and dried to prepare an extract; (3) Epimedium is boiled in water for 2-5 times and extracted, with the weight ratio of water and Epimedium making 10 to 30 every time; the prepared extracts are mixed, filtered and concentrated, alcohol is added to the concentrated solution to ensure the alcohol concentration 60% to 80 %; the solution is cooled and filtered; the prepared filtrates are concentrated; water is added to the concentrated solution to be mixed to homogeneous, cooled and filtered; the prepared filtrate is introduced into the column absorber with macroporous resin to be eluted with the aqueous eluant and alcohol 40 % to 60%; the eluate is collected and decontaminated, then concentrated and dried up to prepared Epimedium extract; (4) the mixed extracts prepared at the stages (2) and (3) are mixed with a usual adjuvant to prepare a medical composition.;EFFECT: invention allows implementing specified object matter.;6 cl, 3 tbl, 3 ex
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机译:领域:药物;物质:组合物包含以1-10重量份的人参和1-10重量份的淫羊ium的比例从草药中提取的活性成分。注射剂,胶囊剂,丸剂,片剂或口服液。执行以下步骤:(1)称量草药; (2)将人参用60%至90%的酒精提取1-3次;将制备的提取物混合,过滤并浓缩;将纯净水加入浓缩溶液中,混合成均匀溶液;然后将混合物冷却并过滤;将稀释的滤液引入柱吸收器中,用含水洗脱液和70%至90%的酒精洗脱;收集洗脱液并进行去污,浓缩和干燥以制备提取物; (3)淫羊ium在水中煮沸2-5次,提取,水与淫羊weight的重量比每次为10-30。将制备的提取物混合,过滤并浓缩,将醇加入浓缩溶液中,以确保醇浓度为60%至80%。将溶液冷却并过滤;将制备的滤液浓缩;向浓缩溶液中加水,混合均匀,冷却并过滤。将制备的滤液与大孔树脂一起引入柱吸收器中,用含水洗脱液和40%至60%的醇洗脱。收集洗脱液并进行去污,然后浓缩并干燥以制备淫羊med提取物。 (4)将在步骤(2)和(3)中制备的混合提取物与常规佐剂混合以制备药物组合物。效果:本发明允许实现指定的目标物质; 6 cl,3 tbl,3 ex
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