INACTIVATED COMBINED VACCINE AGAINST CATTLE INFECTIOUS RHINOTRACHEITIS, PARAINFLUENZA-3, VIRUS DIARRHOEA, RESPIRATORY SYNCYTIAL ROTA- AND CORONAVIRAL DISEASE

摘要

FIELD: medicine.;SUBSTANCE: invention refers to biotechnology. The vaccine contains an active substance and target additives. The active substance is presented with mixed inactivated suspension of cattle infectious rhinotracheitis virus strain, SVC (State Virus Collection) No. 2333, Herpesviridae family, Alphaherpesviridae subfamily; inactivated suspension of cattle parainfluenza-3 virus strain, SVC No. 2334, Paramixoviridae subfamily, Paramixovirus genus; inactivated suspension of cattle diarrhoea virus strain, SVC No. 2336, Flaviviridae family, Pestivims genus; inactivated suspension of cattle respiratory syncytial disease, SVC No. 2335, Pneumoviridae subfamily, Pneumovirus genus; inactivated suspension of cattle rotavirus strain, SVC No. 2337, Reoviridae family, Rotavirus genus, inactivated suspension of cattle coronavirus strain, SVC No. 2338, Coronaviridae family, Coronavirus genus, with activity of each strain not less than 10^6.5 "ТЦД₅₀" per 1 cm³ of the vaccine.;EFFECT: vaccine is better than common vaccines in the spectrum of specific protection and effectiveness for tolerant group of animals, duration of intense immunity, harmlessness for incalvers and newborn calves, stability of biological properties throughout 18 months (follow-up period).;3 cl, 12 tbl, 6 ex