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DIAGNOSTIC TECHNIQUE FOR POSTTRAUMATIC STRESS DISORDER MODELLED IN LABORATORY ANIMALS

机译:实验室动物模型的创伤后应激障碍诊断技术

摘要

FIELD: medicine.;SUBSTANCE: laboratory animals are exposed to "recalling" stress. The diagnostics is based on blood parametres in the hormone samples taken in the pre set time with the blood samples drawn in 30 and 60 minutes after the stress. Each sample is analysed for corticosterone concentration. And if in the 60-minute sample, it is lower than in the 30-minute sample, posttraumatic stress disorder in an animal unit is diagnosed.;EFFECT: method requires introduction of an exogenous hormone, thereby enabling to observe an indicator via the level of endogenic glucocorticoids, and to diagnose specific disorders of fast regulation of hypophysial-adrenocortical systems.;2 dwg, 1 ex
机译:领域:医学。;物质:实验动物暴露于“缓解”压力中。诊断基于在预设时间内采集的激素样本中的血液参数,并在应激后30分钟和60分钟内抽取血液样本。分析每个样品的皮质酮浓度。并且如果在60分钟的样本中低于30分钟的样本,则可以诊断出动物单位的创伤后应激障碍。效果:该方法需要引入外源激素,从而可以通过水平观察指标内源性糖皮质激素的诊断,并诊断下体-肾上腺皮质系统快速调节的特定疾病。; 2 dwg,1 ex

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