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METHOD OF OPTIMISATION OF HODGKIN'S LYMPHOMA OF IIIA STAGE TREATMENT IN ADULTS

机译:成人霍奇金淋巴瘤IIIA期治疗的优化方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to oncology and can be used for optimisation of Hodgkin's lymphoma of IIIA stage treatment in adults. Method is realised in the following way. In case there are no symptoms of intoxication, patients with histological subtype nodular sclerosis and with histological grade at which 75% and more of cellular nodules contain only dispersed Berezovsky-Stenberg cells located on rich in lymphocytes mixed cellular or fibrohistiocytic background, 2-3 cycles of introductory combined chemical therapy are carried out according to schemes MOPP, MOPPABV or ABVD. After that total or subtotal irradiation of lymphatic nodules is performed.;EFFECT: application of invention allows to determine indications for chemical-radiological therapy taking into account versions of histological structure of tumour, ensures long-term recurrence-free survival rate and reduces treatment toxicity.;2 ex
机译:技术领域本发明涉及医学,即肿瘤学,可用于优化成人IIIA期治疗的霍奇金氏淋巴瘤。该方法通过以下方式实现。如果没有中毒症状,组织学亚型结节性硬化症且组织学分级为75%或更多的细胞结节仅包含分散的Berezovsky-Stenberg细胞,其位于富含淋巴细胞的混合细胞或纤维组织细胞背景下,需要2-3个周期根据方案MOPP,MOPPABV或ABVD进行联合化学疗法的评估。在进行了淋巴结节的全部或次要照射之后;效果:本发明的应用允许考虑到肿瘤的组织学结构版本来确定化学放射疗法的适应症,确保长期无复发生存率并降低治疗毒性。; 2前

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