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Repair and treatment of bone defects using drug-induced cells made from chondrocytes capable of hypertrophication and a scaffold
Repair and treatment of bone defects using drug-induced cells made from chondrocytes capable of hypertrophication and a scaffold
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机译:使用能够肥大的软骨细胞和支架制成的药物诱导细胞修复和治疗骨缺损
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摘要
The present invention provides a method of inducing undifferentiated cells into induced osteoblasts. The method includes: A) a step of providing an induced osteoblast differentiation inducing agent obtained by culturing chondrocytes capable of hypertrophication in a differentiation agent producing medium containing dexamethasone, -glycerophosphate, ascorbic acid and a serum component; and B) a step of culturing the undifferentiated cells in an undifferentiated cell culture medium containing the induced osteoblast differentiation inducing agent and a medium component, to differentiate the undifferentiated cells into the induced osteoblasts.
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