MEASURES AND PROCEDURES FOR THE PRESENTATION OF COMPETITION

摘要

Procedure for diagnosis and/or prediction of early joint destruction and/or accelerated joint destruction, including the determination of the presence of at least one nucleic acid sequence selected from the group of:(a) a nucleic acid sequence encoding an IL-4 receptor (IL-4R) which contains a mutation of position 465 of the nucleotide sequence of the wild type IL-4R shown in SEQ ID NO: 1, replacing the nucleotide A at the position;(b) a nucleic acid sequence encoding an IL-4 receptor (IL-4R) which contains a mutation of position 465 of the nucleotide sequence of the wild type IL-4R shown in SEQ ID NO: 1, where the nucleotide A is replaced by the nucleotide G;(c) a nucleic acid sequence encoding an IL-4R receptor (IL-4R), the IL-4R encoding a valine at the position 75-N shown in SEQ ID: 2;(d) a nucleic acid sequence encoding an IL-4R receptor (IL-4R), the IL-4R being shown on the one in SEQ ID NO: 2...