new impfstoffzusammensetzung and use of surfactants as immunadjuvans

摘要

Use of a surfactant or its mixture comprising alkoxylated derivatives of corn oil, having overall hydrophilic-lipophilic balance (HLB) number of 12-13.5, preferably ethoxylated derivatives of corn oil having an essential oil (EO) number of 20-40, for the manufacture of an immune adjuvant in a composition in the form of aqueous solution comprising at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence, is claimed. An independent claim is included for a composition in the form of an aqueous solution comprising: (i) at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence and, (ii) the surfactant or its mixture comprising alkoxylated derivative of corn oil or its mixture with an overall HLB number of 10-14, as an immune adjuvant, provided that the HLB number is different from 10. ACTIVITY : Cytostatic; CNS-Gen.; Respiratory-Gen.; Antimicrobial; Virucide; Antibacterial; Antiparasitic. MECHANISM OF ACTION : Vaccine.