highly efficient, retroviraler vector, which is genetically manufactured, cellular, nichtkodierende sequences, which comprise a spleissakzeptor includes

摘要

The present invention provides a safe and highly efficient retroviral vector derived from the MLV (murine leukemia virus) for use in gene therapy, which lacks viral coding sequences but contains the genetically engineered EF Ialpha non-coding sequence harboring splicing acceptor.