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process for the production of lamotrigine and its intermediate dichlorbenzoylchlorid 2.3 -
process for the production of lamotrigine and its intermediate dichlorbenzoylchlorid 2.3 -
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机译:拉莫三嗪及其中间体二氯苯甲酰氯2.3的生产方法
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摘要
A method for preparing 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, commonly known as lamotrigine, is disclosed. A method of preparing the intermediate, 2,3-dichlorobenzoyl chloride, by photochlorination of 2,3-dichlorobenzotrichloride followed by hydrolysis is also disclosed. The intermediate may then be used in the preparation of lamotrigine.
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