TARGETING MODULATORS OF CES1 AND / OR CES3 IN THE TREATMENT OF ACNE, SEBORRHEA DERMATITIS OR HYPERSEBORRHEA

摘要

The invention relates to an in vitro or in vivo method for screening candidate compounds for the preventive or curative treatment of acne, seborrheic dermatitis or skin disorders associated with hyperseborrhoea comprising determining the capacity of a compound to modulate the expression or the activity of the carboxylesterase 1 (CES1) and / or carboxylesterase 3 (CES3) proteins.