OPTICAL ISOMER OF TENATOPRAZOLE AND USE THEREOF IN MEDICAL TREATMENT

摘要

PPROBLEM TO BE SOLVED: To provide an antiulcer drug having a prolonged activity retention time, unlike proton pump inhibitors such as omeprazole or lansoprazole. PSOLUTION: An optically active material of tenatoprazole, (+) and (-)-5-methoxy-2-ä[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl}-1H-imidazo[4,5-b]pyridine, and a medical drug composition containing the same are useful for the treatment of atypical esophagus disorders such as gastroesophageal reflux disease, bleeding in the digestive system and indigestion. PCOPYRIGHT: (C)2011,JPO&INPIT