METHOD OF PREPARATION OF FORMULATION OF PEPTIDE ANGIOTENSIN-(1-7) AND ANALOG, AGONIST, AND ANTAGONIST THEREOF, USING CYCLODEXTRIN, LIPOSOME AND BIODEGRADABLE POLYMER, AND/OR THEIR MIXTURE AND PRODUCT

摘要

PPROBLEM TO BE SOLVED: To provide a medical preparation for the research or treatment of arterial hypertension of warm-blooded animals and other cardiovascular disorder and its concomitant disease, wound, burn wound, actinic erythema, tumor, diabetes, mobility of sperm, nephropathia, gastrointestinal and gynecological disorder, neoangiogenesis, vascular formation, alopecia and blood disorder or for the research of G protein conjugated receptor MAS as a ligand. PSOLUTION: The present invention provides the medical preparation of D-AlaSP7/SP-angiotensin-(1-7)(A-779) and its analogs and derivatives, D-ProSP7/SP-angiotensin-(1-7) and its analogs or derivatives, and Ang-(1-7) analogs or derivatives using hydrophilic cyclodextrin, liposome, a biodegradable polymer and its derivatives. PCOPYRIGHT: (C)2011,JPO&INPIT