Method and system for vacuum driven differential mobility spectrometer / mass spectrometer tunable selectivity and with a resolution

摘要

A differential mobility analyzer, is sealed at least partially differential mobility analyzer, and comprising a mass spectrometer in communication differential mobility analyzer and the fluid, the mass spectrometer system, associated methods to provide with. Mass spectrometer system, a) through a step of maintaining a differential mobility spectrometer with internal operating pressure, b) providing a ion differential mobility spectrometer, c) a differential mobility analyzer Te to draw gas stream containing ions into the vacuum chamber, maintaining a mass spectrometer at a lower vacuum pressure than the internal operating pressure, d) for changing the gas flow rate through the differential mobility analyzer the, can become operable to perform the steps of modifying the gas flow between the differential mobility spectrometer and the mass spectrometer, the method may include these steps.