TOXOPLASMA PROTOZOAN STRAIN FOR ENABLING IMMEDIATE FUNCTION INHIBITION OF PROTOZOAN PROTEIN KINASE

摘要

PPROBLEM TO BE SOLVED: To provide a toxoplasma protozoan strain for enabling function inhibition of protein kinase by a conditioned knockout using a protein kinase inhibitor derivative in a toxoplasma protozoan. PSOLUTION: The toxoplasma protozoan is obtained by introducing a mutation to a protein kinase having sensitivity to a specific protein kinase inhibitor derivative existing in a toxoplasma protozoan to make the protein kinase insensitive to the derivative, eliminating the protein kinase having sensitivity to the specific protein kinase inhibitor derivative, meanwhile, introducing a mutation that provides sensitivity to the specific protein kinase inhibitor derivative to a protein kinase desired to be subjected to a function analysis. PCOPYRIGHT: (C)2011,JPO&INPIT