The formulation for pH measurement inside stomach and pH measurement modulo null inside the stomach which uses

摘要

The present invention provides a formulation capable of measuring the gastric pH in a simple and non-invasive manner, for example, a formulation capable of measuring the pH in the stomach with expiration, and an in vivo pH measurement method using the same. The formulation of the present invention can be prepared by coating a composition comprising a compound labeled with an isotope (13C, 14C, 15N or 18O) with a pH dependent solubility agent.