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Antibody that recognizes GM1 ganglioside-binding amyloid β protein, and DNA encoding the antibody
Antibody that recognizes GM1 ganglioside-binding amyloid β protein, and DNA encoding the antibody
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机译:识别结合GM1神经节苷脂的淀粉样β蛋白的抗体和编码该抗体的DNA
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摘要
It is intended to provide an antibody efficacious in diagnosing, preventing or treating Alzheimer's disease, DNA encoding the antibody, a method of screening a drug and drugs. The amino acid sequence and the gene sequence of the variable region of an antibody, which specifically recognizes a GM1 ganglioside-bound amyloid beta -protein occurring in the early stage of beta -amyloid fibril formation, are determined. Based on the data of the amino acid sequence and the gene sequence thus obtained, an antibody is designed.
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