Polymorphism of chromosome 9 involved in the premature graying

摘要

The use of one, a method for the diagnosis of a predisposition to premature canities, the present invention, the four markers for diagnostic purposes and a kit for diagnosing at least one of rs365297 and rs306534, rs3739902, rs575916 SNP four markers to make the diagnosis Method for the diagnosis of a predisposition to premature canities based on haplotypes defined use of means for detecting the alleles, the rs3739902, rs2583805 and rs377090 markers, as well as for the diagnosis of a predisposition to premature canities in non-human mammal poly at least one corresponding to the area of ​​all or part of non-human mammalian animal homologous to the region of human chromosome 9, which is defined by the rs365297 SNP and markers rs306534, further contains a contiguous nucleotides 18 least regarding the use of nucleotide fragment.