首页> 外国专利> His-Ser-Leu as a therapeutic agent used alone or in combination with a peptide of Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH -Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe peptide use

His-Ser-Leu as a therapeutic agent used alone or in combination with a peptide of Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH -Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe peptide use

机译:作为治疗剂的His-Ser-Leu单独或与Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH的肽结合使用- Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe肽使用

摘要

The present invention is directed to the use of the peptide compound His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
机译:本发明涉及肽化合物His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe作为预防和/或治疗癌症的治疗剂的用途,自身免疫性疾病,纤维化疾病,炎性疾病,神经退行性疾病,传染病,肺部疾病,心脏和血管疾病以及代谢性疾病。而且,本发明涉及药物组合物,其优选为冻干物或液体缓冲溶液或人工母乳制剂或母乳替代物形式,其包含肽His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro- Asp-Lys-Phe任选地与至少一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂和/或稀释剂一起。

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