Use of at least one saposin level for diagnosing or monitoring lysosomal storage disorders in a subject

摘要

(57) Abstract As for this invention, the method where it diagnoses or monitors lysosome storage disorder, or is offered saposhin and LAMP in the sample of the patient and/or on the basis of the detection of level of - gurukoshidaze. Shows saposhin and/or the level where LAMP rose obstacle. The level where gurukoshidaze rose shows the lysosome storage disorder of several types, the level which gurukoshidaze decreases shows the lysosome storage disorder of other type. Regarding several methods, profile of rise of saposhin, LAMP and gurukoshidaze which differ makes the distinction between lysosome storage disorders of the type which differs possible.