PROBLEM TO BE SOLVED: To provide a system and a method for acquiring a biopsy tissue sample.SOLUTION: A targeting guide device is configured to support a biopsy device 14. The guide device includes a first plate and a second plate. The biopsy device 14 may be supported by either the first plate or the second plate. The targeting guide device is also configured to be secured to a grid plate 96, which is situated adjacent the tissue to be biopsied. The grid plate 96 includes openings that are defined by grid walls. Either or both of the first plate and the second plate have a slot within which a grid wall may be disposed so as to secure placement of the targeting guide device. In addition, either or both of the first plate and the second plate have an access hole through which a biopsy device 14 may be inserted. A flanged insert may be positioned through the access hole to provide further support for the biopsy device 14.
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