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Bicyclic carbohydrate compounds useful for the treatment of infections caused by species belonging to the Flaviviridae family such as hepatitis C and bovine viral diarrhea viruses
Bicyclic carbohydrate compounds useful for the treatment of infections caused by species belonging to the Flaviviridae family such as hepatitis C and bovine viral diarrhea viruses
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机译:双环碳水化合物化合物可用于治疗由黄病毒科的物种引起的感染,例如丙型肝炎和牛病毒性腹泻病毒
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摘要
We describe the use of bicyclic carbohydrates for the treatment of hepatitis C virus infections. Different bicyclic carbohydrates were tested in vitro against DNA-viruses, retro-viruses and Flaviviridae sp., an important family of human and animal RNA pathogens. Significant activity was observed against the bovine viral diarrhea virus (BVDV). As pestiviruses, such as BVDV, share many similarities with hepatitis C virus (HCV), the bicyclic carbohydrates in general and the preferred bicyclic carbohydrates more specifically are expected to be a treatment for hepatitis C viral infections.
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