首页> 外国专利> Novel aryl- {4-halo-4-(heteroarylmethylamino) methyl piperidin-1-yl} methanone derivatives, process for their preparation and their use as medicaments

Novel aryl- {4-halo-4-(heteroarylmethylamino) methyl piperidin-1-yl} methanone derivatives, process for their preparation and their use as medicaments

机译:新的芳基-{4-卤代-4-[(杂芳基甲基氨基)甲基]哌啶-1-基}甲酮衍生物,其制备方法和用作药物

摘要

1-Benzoyl-4-(N-(heteroarylmethyl)-aminomethyl)-piperidine derivatives (I) are new. Piperidine derivatives of formula (I) and their tautomers and optionally hydrated addition salts with mineral or organic acids are new. X, Y = CH or N; A = Me, CH2F, CN, OH, OMe, Cl or F; G = Cl or F; D = H, Cl, F, CN or CF3; and E = H, F or Cl; Provided that if A = Me and X = Y = CH, then G is Cl.
机译:1-苄基-4-(N-(杂芳基甲基)-氨基甲基)-哌啶衍生物(I)是新的。式(I)的哌啶衍生物及其互变异构体以及任选的与无机或有机酸的水合加成盐是新的。 X,Y = CH或N; A = Me,CH2F,CN,OH,OMe,Cl或F; G = Cl或F; D = H,Cl,F,CN或CF3;并且E = H,F或Cl;假设如果A = Me且X = Y = CH,则G为Cl。

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