POROUS CERAMIC SCAFFOLD HAVING AN ORGANIC/INORGANIC HYBRID COATING LAYER CONTAINING BIOACTIVE FACTOR AND METHOD THEREOF

摘要

A method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid composite coating layer containing a bioactive factor is disclosed. The method includes; forming a porous ceramic scaffold, mixing a silica xerogel and a physiologically active organic substance to prepare an organic/inorganic hybrid composite, adding a bioactive factor to the organic/inorganic hybrid composite, and filling the organic/inorganic composite containing the bioactive factor into a pore structure of the porous ceramic scaffold, thereby coating the porous ceramic scaffold. In accordance with the method, the porous ceramic scaffold may be uniformly coated with the organic/inorganic hybrid composite while maintaining an open pore structure, and stably discharge the bioactive factor over a long period of time.