ROBUST MOSAICING METHOD, NOTABLY WITH CORRECTION OF MOTION DISTORTIONS AND TISSUE DEFORMATIONS FOR A VIVO FIBERED MICROSCOPY

摘要

The present invention concerns a mosaicing method taking into account motion distortions, irregularly sampled frames and non-rigid deformations of the imaged tissue. The invention relates to a method for mosaicing frames from a video sequence acquired from a scanning device such as a scanning microscope, the method comprising the steps of:a) compensating for motion and motion distortion due to the scanning microscope,b) applying a global optimisation of inter-frame registration to align consistently the framesc) applying a construction algorithm on the registered frames to construct a mosaic, andd) applying a fine frame-to-mosaic non rigid registration.;The method is based on a hierarchical framework that is able to recover a globally consistent alignment of the input frames, to compensate for the motion distortions and to capture the non-rigid deformations.