An introducing position arrangement unit arranges a position of a cell into which a substance is introduced, of the cells in a culture dish mounted on a stage, specified by a specification unit to a predetermined cell manipulation position in a viewing field of an observation unit by stage driving. A cell manipulation unit introduces an introduction substance mixed in a culture fluid in the culture dish into the cell by making a hole on a cell membrane of the cell moved to the predetermined cell manipulation position. A diagram display unit displays a diagram associated with an observation range which is a range of the culture dish observable by the observation unit and also displays a cell manipulation range which is a cell manipulation enabled range and a position currently observed by the observation unit to be superimposed on the diagram associated with the observation range.
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