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Methods of Predicting Cancer Risk Using Gene Expression in Premalignant Tissue

机译:利用癌前组织中基因表达预测癌症风险的方法

摘要

The present disclosure provides methods for assessing a patient's cancer risk and/or recurrence risk, which methods comprise assaying, in a biological sample obtained from the gastrointestinal (GI) tract of the patient, an expression level of a risk gene. The present disclosure also provides methods involving a cancer risk/recurrence risk sequence, i.e. the V600E mutation of the BRAF gene, which is useful for assessing cancer risk and/or recurrence risk in a patient.
机译:本公开提供了用于评估患者的癌症风险和/或复发风险的方法,该方法包括在从患者的胃肠(GI)道获得的生物学样品中测定风险基因的表达水平。本公开还提供了涉及癌症风险/复发风险序列,即BRAF基因的V600E突变的方法,其可用于评估患者的癌症风险和/或复发风险。

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