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ULTRA-SENSITIVE DETECTION OF MOLECULES USING DUAL DETECTION METHODS
ULTRA-SENSITIVE DETECTION OF MOLECULES USING DUAL DETECTION METHODS
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机译:使用双重检测方法进行分子的超灵敏检测
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摘要
Described herein are systems and methods for the detection of and/or determination of a measure of the concentration of analyte molecules or particles in a fluid sample. In some cases, the systems and methods employ techniques to reduce or limit the negative effects associated with non-specific binding events. Certain methods of the present invention involve associating the analyte molecules at least a first type of binding ligand and at least a second type of binding ligand, and spatially segregating the analyte molecules into a plurality of locations on a surface. The presence of an analyte molecule at or in a location may be determined by determining the presence of both the first type of binding ligand and the second type of binding ligand.
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