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STUDY OF POLYMER MOLECULES AND CONFORMATIONS WITH A NANOPORE
STUDY OF POLYMER MOLECULES AND CONFORMATIONS WITH A NANOPORE
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机译:纳米分子对聚合物分子和构象的研究
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摘要
The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.
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