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Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same

机译:具有较高临界溶液温度的聚合物水溶液,用该聚合物改性的颗粒的水分散体及其储存方法

摘要

It is intended to provide an aqueous solution of a thermoresponsive polymer and an aqueous dispersion of a thermoresponsive particle, which show an upper critical solution temperature (UCST) and are capable of maintaining a dissolved state and a dispersed state, respectively, even if they are stored for a long period of time at a temperature at which a ligand such as an antibody or an antigen is not inactivated. A UCST lowering agent is incorporated in a predetermined amount in an aqueous solution of a thermoresponsive polymer which shows a UCST in a state of containing water or an aqueous dispersion of a thermoresponsive particle containing the polymer, thereby lowering the UCST of the aqueous solution or aqueous dispersion to less than the storage temperature, and the resulting aqueous solution or aqueous dispersion is stored.
机译:本发明旨在提供一种热响应性聚合物的水溶液和热响应性颗粒的水分散体,其显示出较高的临界溶液温度(UCST),并且即使它们分别处于溶解状态和分散状态,也能够保持溶解状态和分散状态。在抗体或抗原等配体未失活的温度下长时间保存。将预定量的UCST降低剂掺入在含水状态下显示UCST的热响应性聚合物的水溶液或包含该聚合物的热响应性颗粒的水分散体中,从而降低水溶液或水的UCST。分散至低于储存温度,然后储存所得的水溶液或水分散体。

著录项

  • 公开/公告号US7976728B2

    专利类型

  • 公开/公告日2011-07-12

    原文格式PDF

  • 申请/专利权人 MASARU EGUCHI;NORIYUKI OHNISHI;

    申请/专利号US20080147269

  • 发明设计人 NORIYUKI OHNISHI;MASARU EGUCHI;

    申请日2008-06-26

  • 分类号C08F20/54;C08F6/06;

  • 国家 US

  • 入库时间 2022-08-21 18:12:08

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