首页>
外国专利>
Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
展开▼
机译:由具有水凝胶聚合物的纤维基质形成的可扩张构件,用于腔内药物递送
展开▼
页面导航
摘要
著录项
相似文献
摘要
An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the hydrogel polymer having a therapeutic agent therein. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is released from the hydrogel polymer and delivered to the desired treatment site.
展开▼