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Pharmaceutical Combinations Comprising Specified Age Breaker and Further Drugs, I.A. Antihypertensive Drugs, Antidiabetic Drugs Etc.

机译:包含特定年龄限制者和其他药物的药物组合,I.A。抗高血压药,抗糖尿病药等。

摘要

The present invention relates to a combination, such as a combined preparation or pharmaceutical composition comprising: (a) compound of formula (I), and/or (II) or a pharmaceutically acceptable salt thereof; (b) at least one therapeutic agent selected from the group consisting of: an antihypertensive agent; an antidiabetics agent; a hypolipidemic agent; an antiplatelet agent; an antiobesity agent; an antithrombotic agent; an agent for diabetic vascular complications; and an agent for treatment of heart failure; or a pharmaceutically acceptable salts thereof, optionally in presence of a pharmaceutically acceptable carrier for separate, simultaneous or sequential use. The present invention also relates to a use of such combination for the treatment of mammal including human being. R1, R2, R3, R1, R2, R3, R4, R5, X, Y, A and B and m are as defined in the specification.; embedded image
机译:本发明涉及一种组合,例如组合制剂或药物组合物,其包含:(a)式(I)的化合物和/或(II)的化合物或其药学上可接受的盐; (b)至少一种选自下列的治疗剂:抗高血压药;和抗糖尿病药;降血脂药;抗血小板药;抗肥胖药;抗血栓药;糖尿病血管并发症的药物;和治疗心力衰竭的药剂;或其药学上可接受的盐,任选地在药学上可接受的载体存在下用于分开,同时或顺序使用。本发明还涉及这种组合在治疗包括人类在内的哺乳动物中的用途。 R 1 ,R 2 ,R 3 ,R 1 ,R 2 , R 3 ,R 4 ,R 5 ,X,Y,A和B和m如规范中所定义。 “嵌入式图像”

著录项

  • 公开/公告号US2011034378A1

    专利类型

  • 公开/公告日2011-02-10

    原文格式PDF

  • 申请/专利号US20090735472

  • 申请日2009-01-21

  • 分类号A61K31/4425;A61K31/4545;A61K31/4439;A61K31/4436;A61K31/55;A61K31/472;A61K31/675;A61K31/549;A61K31/397;A61K38/26;A61K38/28;A61K31/704;A61P9/04;A61P9/12;A61P9/10;A61P9;A61P13/12;A61P3/10;A61P3/04;A61P7/02;C07D213/86;C07D213/87;C07D405/14;C07D401/12;C07D401/06;C07D409/06;C07D417/06;

  • 国家 US

  • 入库时间 2022-08-21 18:10:56

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