embedded image "/> THIENOPYRIDONE DERIVATIVES AS AMP- ACTIVATED PROTEIN KINASE (AMPK) ACTIVATORS
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THIENOPYRIDONE DERIVATIVES AS AMP- ACTIVATED PROTEIN KINASE (AMPK) ACTIVATORS

机译:噻吩基吡啶衍生物作为安培活化的蛋白激酶(AMPK)激活剂

摘要

The present invention relates to compounds of formula (I) wherein R1, R2 and B1, B2 are as defined in claim 1, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention of diseases and disorders modulated by AMP agonists. The invention is also directed to intermediates and to a method of preparation of compounds of formula (I).; embedded image
机译:本发明涉及式(I)的化合物,其中R 1 ,R 2 和B 1 ,B 2 1 所定义,包括其药物组合物,以及它们在治疗和/或预防由AMP激动剂调节的疾病和病症中的用途。本发明还涉及中间体和式(I)化合物的制备方法。 “嵌入式图像”

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