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Antisense modulation of stearoyl-CoA desaturase expression

机译:硬脂酰辅酶A去饱和酶表达的反义调节

摘要

Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
机译:提供了用于调节硬脂酰辅酶A去饱和酶表达的反义化合物,组合物和方法。该组合物包含靶向编码硬脂酰-CoA去饱和酶的核酸的反义化合物,特别是反义寡核苷酸。提供了使用这些化合物调节硬脂酰辅酶A去饱和酶表达并治疗与硬脂酰辅酶A去饱和酶表达有关的疾病的方法。

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