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Use of multispecific, non-covalent complexes for targeted delivery of therapeutics
Use of multispecific, non-covalent complexes for targeted delivery of therapeutics
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机译:多特异性非共价复合物用于靶向治疗的用途
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摘要
Embodiments of the invention relate to a method for treating target cells, tissues or pathogens in a subject, comprising administering a non-covalently bound complex which comprises a multispecific targeting protein and a hapten-enzyme covalent conjugate, followed by administration of a prodrug that is converted to an active drug by the enzyme. Other embodiments of the invention further relate to kits comprising the non-covalently bound complex or the components to prepare the complex.
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