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Single pot process for the regioselective synthesis of neolignan framework asarones
Single pot process for the regioselective synthesis of neolignan framework asarones
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机译:单锅法用于区域选择性合成新木脂素骨架麻黄素
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摘要
The present invention provides a single pot process for the regioselective synthesis of neolignan framework [3(R)-Ethyl-2(S)-methyl-3-(2″,4″,5″-trimethoxyphenyl)-1-(2′,4′,5′-trimethoxyphenyl)propane from toxic β-isomer rich asarone using montmorillonite acidic clay by employing microwave organic reaction enhancement (MORE) chemistry. This may be useful as versatile synthetic protocol for the synthesis of a large number of lignan and neolignan frameworks.
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