Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor

摘要

A saccharide-measuring fluorescence sensor substance including a copolymer of at least the following two compounds (I) and (II) is provided:(I) a fluorescent monomer compound represented by the following formula (1): formula (1); wherein:Q, Q′ and D³ may be the same or different, may be combined together into a fused ring, and are each a substituent selected from the group consisting of a hydrogen atom, a halogen atom, a hydroxyl group, and substituted or unsubstituted alkyl, acyl, oxyalkyl, carboxyl, carboxylate ester, carboxamido, cyano, nitro, amino and aminoalkyl groups; andD¹, D² and D⁴ each represent a substituent, wherein at least one of D¹, D² and D⁴ is a substituent group comprising a vinyl group at an end thereof, and wherein the substituent group comprising a vinyl group at an end thereof enables the fluorescent monomer compound to be soluble in water, and(II) at least one hydrophilic, polymerizable monomer having a vinyl group.