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Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof

机译：卡他莫拉菌外膜蛋白106多肽，基因序列及其用途

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The invention discloses the Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding OMP106 polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals. 展开▼

机译：本发明公开了卡他莫拉氏菌外膜蛋白106（OMP106）多肽，由其衍生的多肽（OMP106衍生的多肽），编码OMP106多肽的核苷酸序列以及与OMP106多肽和/或特异性结合的抗体OMP106衍生的多肽。还公开了包含OMP106多肽和/或OMP106衍生的多肽的免疫原性，预防性或治疗性组合物，包括疫苗。本发明还公开了诱导对I M的免疫应答的方法。粘膜炎和 M。动物中的粘膜炎 OMP106多肽和OMP106衍生的多肽。 展开▼

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公开/公告号US7914795B2

专利类型

公开/公告日2011-03-29

原文格式PDF

申请/专利权人 KENNETH TUCKER;LAURA PLOSILA;ULRICH F. TILLMAN;
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申请/专利号US20090541701

发明设计人 KENNETH TUCKER;LAURA PLOSILA;ULRICH F. TILLMAN;
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申请日2009-08-14

分类号A61K39/02;C07K14;

国家 US

入库时间 2022-08-21 18:08:15

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1. 卡他摩拉克菌外膜蛋白—106多肽及其基因序列和用途 [P] . 中国专利： CN100415871C . 2008.09.03

2. 卡他摩拉克菌外膜蛋白－106多肽及其基因序列和用途 [P] . 中国专利： CN1800359A . 2006-07-12

3. MORAXELLA CATARRHALIS OUTER MEMBRANE PROTEIN-106 POLYPEPTIDE, GENE SEQUENCE AND USES THEREOF [P] . 美国专利： US2010021492A1 . 2010-01-28

机译：莫拉氏杆菌外膜蛋白106多肽，基因序列及其用途

4. Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof [P] . 日本专利： JP4401437B2 . 2010-01-20

机译：卡他莫拉菌外膜蛋白106多肽，基因序列及其用途

5. Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof [P] . 美国专利： US7576179B2 . 2009-08-18

机译： 卡他莫拉菌外膜蛋白106多肽，基因序列及其用途

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9. Outer membrane protein B1, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin [O] . A A Campagnari, T F Ducey, C A Rebmann 1996

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