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Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same

机译:具有选择性改变结晶度的聚合物材料的腔内假体及其制造方法

摘要

Methods of manufacturing polymeric intraluminal prostheses include annealing the polymeric material to selectively modify the crystallinity thereof. Annealing may be utilized to selectively modify various properties of the polymeric material of an intraluminal prosthesis, including: selectively increasing the modulus of the polymeric material; selectively increasing the hoop strength of the intraluminal prosthesis; selectively modifying the elution rate (increase or decrease) of a pharmacological agent subsequently disposed on or within the annealed polymeric material; selectively increasing/decreasing stress in the intraluminal prosthesis; and selectively modifying the polymeric material such that it erodes at a different rate.
机译:制造聚合物腔内假体的方法包括使聚合物材料退火以选择性地改变其结晶度。可以利用退火来选择性地改变管腔内假体的聚合材料的各种特性,包括:选择性地增加聚合材料的模量;以及选择性地增加管腔内假体的环向强度;选择性地改变随后置于退火的聚合物材料之上或之内的药理剂的洗脱速率(增加或减少);有选择地增加/减少管腔内假体的应力;并选择性地改性聚合物材料,使其以不同的速率腐蚀。

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