Process for gibberellic acid production with “Fusarium moniliforme” strains

摘要

The present invention provides an improved process for the production of gibberellic acid (GA₃), achieving a yield over 225 g/kg of GA₃ with solid substrate fermentation, and over 15 g/L by submerged fermentation. The method also provides novel substrates, including the use of Jatropha seed cake. The present invention has in particular provided an improved, cost-effective process for the manufacture of GA₃, as the process has a surprisingly high yield of product, achieves the maximal yield in shorter time than other techniques, consumes less energy, and works with very inexpensive substrates. In all, the manufacturing costs are significantly reduced.