Variations of Serum Albumin Binding to anti

摘要

This also refers to ligands (Drugs and compositions comprising Said Nucleic Acid variants, Vectors and hosts.Claim 1: A variant of single immunoglobulin variable Domain anti Albumin Serum (HS) dom7h - 14 (14 dom7h - as shown in Figure 1),The Variant in which comprises at least a mutation in the CDr3 region of 92 to 96 (Numbering of positions according to Kabat) compared with dom7h - 14 and in which the variant is 1 to 8 changes compared with the amino acid sequence of dom7h - 14.